Cynthia Renn, PhD, RN, FAAN

• Chair, Pain and Translational Symptom Science
  Pain and Translational Symptom Science

Location:

Room 731, School of Nursing Building

Phone:

410-706-5736

Email:

• BS, Music Education, Indiana University of Pennsylvania, 1983
• BS, Nursing, York College of Pennsylvania, 1991
• MS, Acute Care Nurse Practitioner, University of Maryland, Baltimore, 1997
• PhD, Neuroscience, University of Maryland, Baltimore, 2004

• Date:

  2016 - 2021

  Title:

  Omics Associated with Self-Management Interventions for Symptoms (OASIS)

  Sponsoring Organization:

  NIH - NINR

  Role:

  Principal

• Date:

  2018 - 2023

  Title:

  Physiological, psychological, and genomic factors that predict the transition from acute to chronic pain in patients with traumatic lower extremity fracture

  Sponsoring Organization:

  NIH NINR

  Role:

  Principal

• Title:

  Neurophysiological and transcriptomic predictors of chronic low back pain: towards precision pain management (NEAT Study)

  Sponsoring Organization:

  NIH - NINR

  Role:

  Principal

• Title:

  Studying the Role of Sensory Neuron Activity, BDNF Expression, and Central Sensitization and the Effects of Curcumin and Exercise on those Processes in Al-induced Arthralgia Using a New Mouse Model

  Sponsoring Organization:

  NIH NINR

  Role:

  Principal

• Chronic pain of various etiologies. Studying the underlying mechanisms associated with the development and persistence of chronic pain. Both preclinical and clinical research.

• Duration:

  2012 - Current

  Title:

  Physiological mechanisms underlying aromatase inhibitor-induced arthralgia

  Description:

  We are examining the physiological mechanisms underlying the development and persistence of AIA using a mouse model. We will pursue this question in a clinical study going forward. This is an ongoing investigation. We are writing several manuscripts reporting our preclinical data.

  Status:

  Writing Results

• Duration:

  2015 - Current

  Title:

  Physiological & psychological mechanisms of chronic pain in lower extremity fracture

  Description:

  We are examining the biobehavioral, psychological, and genetic/genomic predictors of those who will develop chronic pain at the fracture site. This study is ongoing. We submitted an R01 and are awaiting council review.

  Status:

  On-Going

• Renn, C. L. & Dorsey, S. G. (2005, July (3rd Quarter/Summer) 1). The physiology and processing of pain: a review.. AACN clinical issues, 16 (3), 277-90; quiz 413-5.
• Renn, C. L., Lin, L., Thomas, S. & Dorsey, S. G. (2006, July (3rd Quarter/Summer) 31). Full-length tropomyosin-related kinase B expression in the brainstem in response to persistent inflammatory pain.. Neuroreport, 17 (11), 1175-9. doi:10.1097/01.wnr.0000215771.61355.e1
• Dorsey, S. G., Renn, C. L., Carim-Todd, L., Barrick, C. A., Bambrick, L., Krueger, B. K., et al (2006, July (3rd Quarter/Summer) 6). In vivo restoration of physiological levels of truncated TrkB.T1 receptor rescues neuronal cell death in a trisomic mouse model.. Neuron, 51 (1), 21-8. doi:10.1016/j.neuron.2006.06.009
• Dorsey, S. G., Leitch, C. C., Renn, C. L., Lessans, S., Smith, B. A., Wang, X. M., et al (2009, July (3rd Quarter/Summer) 1). Genome-wide screen identifies drug-induced regulation of the gene giant axonal neuropathy (Gan) in a mouse model of antiretroviral-induced painful peripheral neuropathy.. Biological research for nursing, 11 (1), 7-16. doi:10.1177/1099800409332726
• Renn, C. L., Leitch, C. C. & Dorsey, S. G. (2009, October (4th Quarter/Autumn) 29). In vivo evidence that truncated trkB.T1 participates in nociception.. Molecular pain, 5, 61. doi:10.1186/1744-8069-5-61
• Renn, C. L., Leitch, C. C., Lessans, S., Rhee, P., McGuire, W. C., Smith, B. A., et al (2011, October (4th Quarter/Autumn) 1). Brain-derived neurotrophic factor modulates antiretroviral-induced mechanical allodynia in the mouse.. Journal of neuroscience research, 89 (10), 1551-65. doi:10.1002/jnr.22685
• Renn, C. L. & Dorsey, S. G. (2011, January (1st Quarter/Winter) 1). From mouse to man: The efficacy of animal models of human disease in genetic and genomic research.. Annual review of nursing research, 29, 99-112.
• Renn, C. L., Carozzi, V. A., Rhee, P., Gallop, D., Dorsey, S. G. & Cavaletti, G. (2011, April (2nd Quarter/Spring) 26). Multimodal assessment of painful peripheral neuropathy induced by chronic oxaliplatin-based chemotherapy in mice.. Molecular pain, 7, 29. doi:10.1186/1744-8069-7-29
• Dorsey, S. G., Lovering, R. M., Renn, C. L., Leitch, C. C., Liu, X., Tallon, L. J., et al (2012, January (1st Quarter/Winter) 1). Genetic deletion of trkB.T1 increases neuromuscular function.. American journal of physiology. Cell physiology, 302 (1), C141-53. doi:10.1152/ajpcell.00469.2010
• Carozzi, V. A., Renn, C. L., Bardini, M., Fazio, G., Chiorazzi, A., Meregalli, C., et al (2013, January (1st Quarter/Winter) 1). Bortezomib-induced painful peripheral neuropathy: an electrophysiological, behavioral, morphological and mechanistic study in the mouse.. PloS one, 8 (9), e72995. doi:10.1371/journal.pone.0072995

See a full list of published work.

• Year:

  2016

  Title:

  Association of acute pain intensity during immediate hospitalization following injury and subsequent chronic pain

  Conference/Meeting Name:

  American Public Health Association Annual Meeting

  Sponsoring Organization:

  APHA

  Location:

  Denver CO United States

• Year:

  2017

  Title:

  Comparison of quantitative sensory testing and current perception threshold testing results in patients with chronic pain following lower extremity fracture and healthy controls

  Conference/Meeting Name:

  American Pain Society Annual Scientific Meeting

  Sponsoring Organization:

  APS

  Location:

  Pittsburgh PA United States

• Year:

  2018

  Title:

  Cited in Scopus: 0Change in pain scores following administration of analgesics in patients with lower extremity fractures

  Conference/Meeting Name:

  American Pain Society Annual Meeting Scientific

  Sponsoring Organization:

  American Pain Society

  Location:

  Anaheim CA United States

• Preclinical and Clinical Studies of Chronic Pain

• Research
  Physiology
  Pain

University

• Date:

  2018 - 2020

  Organization:

  Faculty Council

  Role:

  Committee Member

• Date:

  2016 - 2019

  Organization:

  Faculty Senate

  Role:

  Committee Member

• Date:

  2016 - 2019

  Organization:

  PhD Curriculum Committee

  Role:

  Committee Member & Chair 2017-2018

• Date:

  2014 - Current

  Organization:

  Center to Advance Chronic Pain Research

  Role:

  Executive Committee Member

Professional

• Date:

  2018 - 2018

  Organization:

  NIH - NINR P29/P30 Study Section (ZNR1 REV M34)

  Role:

  Grant Reviewer/Referee

• Date:

  2018 - 2018

  Organization:

  Medical Research Council, MRC IIB Grant Review

  Role:

  Grant Reviewer/Referee

• Date:

  2017 - 2017

  Organization:

  NIH -NCI

  Role:

  Grant Reviewer/Referee

• Date:

  2020 - 2021

  Organization:

  Nursing Research

  Role:

  Manuscript Reviewer/Referee

• Date:

  2016 - Current

  Organization:

  Supportive Care in Cancer

  Role:

  Manuscript Reviewer/Referee

• Date:

  2016 - Current

  Organization:

  Nursing Outlook

  Role:

  Manuscript Reviewer/Referee

• Date:

  2020 - 2021

  Organization:

  Neuroscience Letters

  Role:

  Manuscript Reviewer/Referee

• Date:

  2016 - Current

  Organization:

  Journal of Neurosciences in Rural Practice

  Role:

  Manuscript Reviewer/Referee

• Date:

  2016 - Current

  Organization:

  Journal of Neurosciences in Rural Practice

  Role:

  Manuscript Reviewer/Referee

Public

• Date:

  2017 - Current

  Organization:

  Committee to Establish Burdick Dog Park in Baltimore City

  Role:

  Committee Member